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Home More Science

New pangenome aims to better represent human diversity

New pangenome aims to better represent human diversity
by Insider Desk
May 15, 2023

A new pangenome, which is a comprehensive collection of human genome sequences, has been released by the Human Pangenome Reference Consortium. 

The pangenome includes genome sequences from 47 people, half of whom have ancestry from sub-Saharan Africa, a third from the Americas, 13% from China, and 2% from Europe, with representation of indigenous people.

The pangenome is a significant improvement over the previous human genome reference, which was based on the genome of a single individual. 

The new pangenome includes more genetic diversity, allowing researchers to understand diseases’ genetic basis better and develop more effective treatments.

“Having one map of a single human genome cannot adequately represent all of humanity,” said Dr. Karen Miga of the University of California, Santa Cruz. “This reboot can be the foundation for the scientific community to have more equitable healthcare in the future.”

The new pangenome is a major step in understanding the human genome better. It will allow researchers to develop more accurate and personalized disease treatments.

Benefits of the new Pangenome

The new pangenome includes more genetic diversity than the previous reference, allowing researchers to understand the genetic basis of diseases better and develop more effective treatments. It will also enable accurate diagnoses of diseases, as they will be able to take into account the genetic diversity of the patient.

Additionally, it will let the researchers develop more personalized treatments for diseases, as they will be able to tailor treatments to the patient’s genetic makeup.

Future of the Pangenome

The Human Pangenome Reference Consortium plans to continue to expand the pangenome by adding more genome sequences from people from all over the world. The goal is to create a pangenome that represents the genetic diversity of the entire human population.

The pangenome has the potential to revolutionize the way we understand and treat diseases. By better understanding the genetic basis of diseases, we can develop more effective treatments tailored to the individual patient. The pangenome is a powerful tool that has the potential to improve the health of people all over the world.

Tags: diseasegenomemedical scienceresearch
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